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☆ A winter weather pattern change is about to bring a wild swing in temperatures to the US
▼ + stars: | 2024-01-19 | by ( Mary Gilbert | ) edition.cnn.com time to read: +9 min

Mark Zaleski/The Tennessean/USA Today Network Snow falls on parked cars in Concord, New Hampshire, on January 16. Monday's caucuses were the coldest ever , with high temperatures below zero across much of the state. Dan Powers/USA Today Network Firefighters rescue a man after his car was stuck in a flooded area in Charlotte, North Carolina, on January 9. Gregg Pachkowski/USA Today Network Snow covers the trees around the Holy Hill Basilica and National Shrine of Mary in Hubertus, Wisconsin, on January 9. Tariq Zehawi/NorthJersey.com/USA Today Network Flooding is seen at an intersection in Spartanburg, South Carolina, on January 9.

Persons: Nature, Nikki Haley, Deb Cram, Andrew Kelly, Mark Zaleski, Snow, Will Lanzoni, Rogelio V . Solis, Amanda Andrade, Rhoades, Reuters Isaac Hammond, Geoff Stellfox, Brandon Bell, Christian Monterrosa, Daniel Cole, Dan Busey, Crews, RJ Sangosti, Jeffrey T, Barnes, Chip Somodevilla, Barbara J, Al Drago, Gary Hershorn, Brendan McDermid, Joseph Prezioso, Jim Vondruska, Andrew Harnik, Eric Seals, Rebecca Zimmerman, Antonio Perez, Zuma Snow, Erin Hooley, Drake, Sam Wolfe, Bryan Woolston, Kelly, Jo St, Aubin, Dan Powers, Peter Zay, Floyd Bennett Field, Spencer Platt, Scott Olson, County Sheriff Tommy Ford, Jaide Garcia, CNN Linda Cox, Gregg Pachkowski, of Mary, Mike De Sisti, Joe Raedle, Michael Gordon, Michael Gordon Workers Brian Henderson, Phil Murphy, Tariq Zehawi, Alex Hicks Jr Organizations: CNN, Omni Mount Washington, USA, Reuters, Mississippi State Capitol, Reuters Isaac Hammond braves, Austin, Bergstrom International Airport, Iowa State Capitol, Getty, Denver International Airport, MediaNews, Denver Post, NFL, Buffalo Bills, Pittsburgh Steelers, AP, Columbus Dispatch, Bloomberg, Corbis, Reuters Storm, AP Vehicles, Chicago Tribune, TNS, Storm Bros, Network Firefighters, County Sheriff, National, of, Milwaukee Journal, People, Michael, Michael Gordon Workers, New, New Jersey Gov, Spartanburg Herald, Chicago, Minneapolis Locations: Bretton Woods , New Hampshire, New, New York, Philadelphia, Baltimore, Washington, Nashville , Tennessee, Concord , New Hampshire, Jackson, Wheeling , Illinois, Washington ,, Malcolm , Iowa, Austin , Texas, Des Moines, AFP, Florence , Alabama, Orchard Park , New York, Williamsburg , Iowa, Worthington , Ohio, Atlantic , Iowa, Hudson, Jersey City , New Jersey, Winthrop , Massachusetts, Ankeny , Iowa, Iowa, Northwestern, Farmington Hills , Michigan, Oak Park , Illinois, Chicago, Bamberg , South Carolina, Annapolis , Maryland, Kaukauna , Wisconsin, Charlotte , North Carolina, Anadolu, Brooklyn , New York, Iowa City , Iowa, Panama City Beach , Florida, Florida's Bay County, County, Myrtle Grove , Florida, Hubertus , Wisconsin, Bay County , Florida, Florida , Alabama, Georgia, Totowa , New Jersey, New Jersey, Spartanburg , South Carolina, Canada, Midwest, Des Moines , Iowa, Minneapolis, Indianapolis, Cleveland, New York City

☆ Northwest faces freezing rain and heavy snow while Arctic blast loosens its grip on eastern US
▼ + stars: | 2024-01-17 | by ( Elizabeth Wolfe | Robert Shackelford | ) edition.cnn.com time to read: +11 min

Mark Zaleski/The Tennessean/USA Today Network Snow falls on parked cars in Concord, New Hampshire, on January 16. Gary Hershorn/Corbis News/Getty Images Snow and ice dust a worker who was removing snow from a sidewalk in Des Moines on January 13. Dan Powers/USA Today Network Firefighters rescue a man after his car was stuck in a flooded area in Charlotte, North Carolina, on January 9. Gregg Pachkowski/USA Today Network Snow covers the trees around the Holy Hill Basilica and National Shrine of Mary in Hubertus, Wisconsin, on January 9. Tariq Zehawi/NorthJersey.com/USA Today Network Flooding is seen at an intersection in Spartanburg, South Carolina, on January 9.

Persons: Nikki Haley, Deb Cram, Andrew Kelly, Mark Zaleski, Snow, Will Lanzoni, Rogelio V . Solis, Amanda Andrade, Rhoades, Reuters Isaac Hammond, Geoff Stellfox, Brandon Bell, Christian Monterrosa, Daniel Cole, Dan Busey, Crews, RJ Sangosti, Jeffrey T, Barnes, Chip Somodevilla, Barbara J, Al Drago, Gary Hershorn, Brendan McDermid, Joseph Prezioso, Jim Vondruska, Andrew Harnik, Eric Seals, Rebecca Zimmerman, Antonio Perez, Zuma Snow, Erin Hooley, Drake, Sam Wolfe, Bryan Woolston, Kelly, Jo St, Aubin, Dan Powers, Peter Zay, Floyd Bennett Field, Spencer Platt, Scott Olson, County Sheriff Tommy Ford, Jaide Garcia, CNN Linda Cox, Gregg Pachkowski, of Mary, Mike De Sisti, Joe Raedle, Michael Gordon, Michael Gordon Workers Brian Henderson, Phil Murphy, Tariq Zehawi, Alex Hicks Jr, Nouran Salahieh, Joe Sutton, Sarah Dewberry, Raja Razek, Jennifer Henderson Organizations: CNN, National Weather Service, Oregon -, . Maine, Police, Rockies, South Washington Cascades, Omni Mount Washington, USA, Reuters, Mississippi State Capitol, Reuters Isaac Hammond braves, Austin, Bergstrom International Airport, Iowa State Capitol, Getty, Denver International Airport, MediaNews, Denver Post, NFL, Buffalo Bills, Pittsburgh Steelers, AP, Columbus Dispatch, Bloomberg, Corbis, Reuters Storm, AP Vehicles, Chicago Tribune, TNS, Storm Bros, Network Firefighters, County Sheriff, National, of, Milwaukee Journal, People, Michael, Michael Gordon Workers, New, New Jersey Gov, Spartanburg Herald Locations: Pacific Northwest, Pacific, Oregon, Northwest, Portland , Oregon, Columbia, Oregon - Washington, Maine, • Buffalo , New York, Buffalo, Tennessee , Mississippi , Arkansas , Kansas, In Tennessee, Knoxville, Washington, Washington , Idaho, Montana, Portland, South, Bretton Woods , New Hampshire, New, New York, Philadelphia, Baltimore, Nashville , Tennessee, Concord , New Hampshire, Jackson, Wheeling , Illinois, Washington ,, Malcolm , Iowa, Austin , Texas, Des Moines, AFP, Florence , Alabama, Orchard Park , New York, Williamsburg , Iowa, Worthington , Ohio, Atlantic , Iowa, Hudson, Jersey City , New Jersey, Winthrop , Massachusetts, Ankeny , Iowa, Iowa, Northwestern, Farmington Hills , Michigan, Oak Park , Illinois, Chicago, Bamberg , South Carolina, Annapolis , Maryland, Kaukauna , Wisconsin, Charlotte , North Carolina, Anadolu, Brooklyn , New York, Iowa City , Iowa, Panama City Beach , Florida, Florida's Bay County, County, Myrtle Grove , Florida, Hubertus , Wisconsin, Bay County , Florida, Florida , Alabama, Georgia, Totowa , New Jersey, New Jersey, Spartanburg , South Carolina, Cincinnati, Detroit, Texas, Gulf, Buffalo , New York, Watertown , Massachusetts, Midwest

CHICAGO (AP) — As the first blast of wintry weather hit Chicago, dozens of migrant families without a place to live were moved off snowy city streets and into the basement of Good Shepherd Lutheran Church in a nearby suburb. The last-minute, temporary solution around 1 a.m. Wednesday, coordinated by volunteers and suburban Oak Park officials, came as Chicago has struggled to house the growing population of asylum-seekers ahead of the deep winter months. City officials have been scouting locations for winterized tents, but City Council members have criticized Johnson's administration for a lack of details. This week, the city publicized its winter efforts, including providing 16 “warming buses” at police stations during overnight hours, and winter coats for new arrivals. Last month, the city touted its partnerships with several outside organizations to provide food, clothing and hygiene items.

Persons: Brandon Johnson, ”, Annie Gomberg, Greg Abbott, They’re, tarps, Gleicy Martinez, ” Martinez, Johnson, Joe Biden, Ronnie Reese, Kathy Nolte, Good Shephard, “, Melissa Perez Winder Organizations: CHICAGO, Good Shepherd Lutheran Church, Republican Texas Gov, Volunteer, Wednesday, Chicago, City, Associated Press Locations: Chicago, Good, Oak, Venezuela, United States, ”, Oak Park

☆ Insight: What happens when a $2 million gene therapy is not enough
▼ + stars: | 2023-08-12 | by ( Deena Beasley | ) www.reuters.com time to read: +13 min

Their experience raises broader questions around other high-cost gene therapies coming to market, sometimes after accelerated regulatory approvals, drug pricing experts said. Gene therapies work by replacing genes – the body's blueprint for its development. The gene Zolgensma delivers instructs the body to make a protein vital for muscle control. If gene therapies do fall short, it becomes harder to justify prices that researchers have argued are already poor value. More recently, the first hemophilia gene therapy approved by the U.S. Food and Drug Administration was priced by CSL Behring at $3.5 million; 26 more gene therapies are in late-stage development, according to IQVIA.

Persons: Elizabeth Kutschke, Ben, Zolgensma, Ben Kutschke, neurologists, Sitra Tauscher, Wisniewski, Ben's, Roger Hajjar, Brigham Gene, Kutschke, Vasant Narasimhan, Stacie Dusetzina, Roche's, Biogen, Roche, Maha Radhakrishnan, Steven Pearson, It's, Sree Chaguturu, Amanda Cook, Weston, Jackson, Cook, Elizabeth, Jerry Mendell, Russell Butterfield, –, Biogen's, Mendell, UMR, Spinraza, Eric Cox, Caroline Humer, Sara Ledwith Organizations: Reuters, U.S, Novartis, IQVIA Institute, Human Data, Novartis Gene Therapies, Mass, Cell Therapy, U.S . Food, Drug Administration, CSL Behring, CSL, Nashville's Vanderbilt University School of Medicine, Clinical, Economic, CVS Health, Aetna, SMA, Nationwide Children's Hospital, University of Utah Health, Children's, UnitedHealth, Thomson Locations: Oak Park, Berwyn , Illinois, Swiss, U.S, Lebanon , Virginia, United States, Columbus , Ohio, Russia, Kazakhstan, Chicago

☆ A Couple Decided to Swap Their Family Home in Pennsylvania for a California Rental. Which One Did They Choose?
▼ + stars: | 2023-03-23 | by ( Livia Albeck-Ripka | ) www.nytimes.com time to read: +2 min

And Mr. Adams, an executive director in cybersecurity for Comcast, was tied down by his job. The pandemic, too, had changed the landscape: Mr Adams was largely working remotely and was free to move. “We thought, are we going to be able to swing it?” Ms. Adams said. “We needed to be near Pepperdine,” Ms. Adams said, adding that other requirements included ample parking (the family has several cars), storage space and a yard. They also wanted at least three bedrooms, two bathrooms and enough space for Mr. Adams to work from home.

"Saturday Night Live's" final show of 2022 doubled as a send-off for Cecily Strong, who exited amid her 11th season and as one of the longest-tenured female cast members. Amid speculation she would depart before the 48th season started in fall, Strong stayed on. Her original characters on the show included Cathy Anne, "Weekend Update" anchor Michael Che's chain-smoking neighbor, which she reprised Saturday in a goodbye sketch. "Actually, I’m a little emo here tonight because truth is I’m here to say goodbye," Cathy Anne said. Cecily Strong as Cathy Anne on "Saturday Night Live."

☆ In Shadow of Chicago Skyline, Urban Anglers Hook Salmon After Salmon
▼ + stars: | 2022-10-20 | by ( Joe Barrett | ) www.wsj.com time to read: 1 min

CHICAGO—Andre Brown went out earlier this month for opening day at one of the most unusual salmon-fishing spots in the country: a lagoon off Lake Michigan with the Chicago skyline for a backdrop. “This place was jam packed,“ said Mr. Brown, a 51-year-old electrician from nearby Oak Park, Ill. ”I got out of my truck and all I see was water splashing. They were just pulling them out like they were grocery shopping at Jewel,” he added, referring to a local grocery chain.

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